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image: Puzzle Me This

Puzzle Me This

By | February 1, 2011

What substance is supposed to have no effect but can make people feel better, has no chance for a big monetary payoff but is worth billions, and is used in virtually every rigorous clinical trial but has no single, universal formulation? 

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image: The Evolution of Credibility

The Evolution of Credibility

By | February 1, 2011

The winding path that an interesting result takes to become a bona fide discovery is just one of the topics covered in this new book on the practice of science.

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image: Appealing Choice

Appealing Choice

By | January 1, 2011

A book is born from pondering why sexual selection was, for so long, a minor component of evolutionary biology.

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Synthetic Spirits

By | January 1, 2011

Can we use science to reduce the harms of alcohol?

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Mail

By | January 1, 2011

A selection of comments from our readers

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image: Watt Fun!

Watt Fun!

By | January 1, 2011

Her doctoral advisor told her to amuse herself, and Fiona Watt has done just that—probing individual stem cells and determining the genes and molecules that direct them to differentiate or cause them to contribute to cancer.

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image: Mining Bacterial Small Molecules

Mining Bacterial Small Molecules

By | January 1, 2011

As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.

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image: Interfering with Cancer

Interfering with Cancer

By | January 1, 2011

MicroRNAs may drive the development of leukemia.

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image: Intestinal Molecular Signaling

Intestinal Molecular Signaling

By | January 1, 2011

Microbes, both good and bad, can exert direct effects on host cells and vice versa. 

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image: Brave New Drugs

Brave New Drugs

By | January 1, 2011

Intoxicating ideas for saving a billion lives

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