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image: The Great Escape

The Great Escape

By Richard P. Grant | February 1, 2011

  Editor's choice in microbiology  

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image: Death or Damage of Dopamine Neurons

Death or Damage of Dopamine Neurons

By Bobby Thomas and M. Flint Beal | February 1, 2011

The hallmark pathology of Parkinson’s disease is the damage and death of dopamine producing neurons in the brain. 

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image: The Genes of Parkinson’s Disease

The Genes of Parkinson’s Disease

By Bobby Thomas and M. Flint Beal | February 1, 2011

The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.

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image: Down but Not Out

Down but Not Out

By Richard P. Grant | February 1, 2011

Cells on standby are surprisingly busy.

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image: Puzzle Me This

Puzzle Me This

By Graeme Stemp-Morlock | February 1, 2011

What substance is supposed to have no effect but can make people feel better, has no chance for a big monetary payoff but is worth billions, and is used in virtually every rigorous clinical trial but has no single, universal formulation? 

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image: Synthetic Spirits

Synthetic Spirits

By David Nutt | January 1, 2011

Can we use science to reduce the harms of alcohol?

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image: Mining Bacterial Small Molecules

Mining Bacterial Small Molecules

By L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | January 1, 2011

As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.

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image: Interfering with Cancer

Interfering with Cancer

By Katherine Hyde and Paul Liu | January 1, 2011

MicroRNAs may drive the development of leukemia.

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image: Intestinal Molecular Signaling

Intestinal Molecular Signaling

By L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | January 1, 2011

Microbes, both good and bad, can exert direct effects on host cells and vice versa. 

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image: Brave New Drugs

Brave New Drugs

By Sarah Greene | January 1, 2011

Intoxicating ideas for saving a billion lives

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