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tag immune rejection neuroscience microbiology

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Jeffrey Perkel | Apr 29, 2001 | 2 min read
Antigen-specific T lymphocytes must be quantified in order to gauge the quality of an immune response. Typically this is accomplished using cytotoxicity assays or limiting dilution analysis (LDA), but these techniques are lengthy and provide indirect quantitation. Also, LDA cannot count nonproliferative cells. In 1996, Stanford University's Mark Davis developed an alternative strategy that overcomes these problems.1 Davis generated phycoerythrin-conjugated tetramers of human lymphocyte antigen (
illustration of neurons in blue with synapses lighting up
Gut Molecule Linked to Decreased Myelination in Mouse Brains
Angie Voyles Askham, Spectrum | Feb 17, 2022 | 4 min read
A study shows that a molecule produced by intestinal microbes can enter the brain and that its presence is also associated with altered brain connectivity.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Updated Mar 8
A healthcare worker holds up three syringes with clear medicine
To Booster or Not: Scientists and Regulators Debate
Jef Akst | Sep 16, 2021 | 7 min read
President Biden’s planned rollout of additional COVID-19 vaccine doses is set to begin next week, but questions remain about who should get them.
Environmental Cues Keep CAR T Cells on Track
Aparna Nathan, PhD | May 25, 2021 | 4 min read
Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Contributors
The Scientist Staff | Sep 1, 2011 | 2 min read
Meet some of the people featured in the September 2011 issue of The Scientist.
AIDS Research Progress Stymied By Narrow Focus, Critics Charge
Franklin Hoke | Jul 10, 1994 | 9 min read
Critics Charge Author: FRANKLIN HOKE, pp.1 Date: July 11,1994 Disputing what they see as unproductive preoccupation with HIV-specific studies, they step up campaign for a `wider window' of research Progress in AIDS research has faltered in the United States since the mid-1980s, according to some scientists, owing to a premature narrowing of the research focus by the scientific and administrative leadership of the National Inst
AIDS Research Progress Stymied By Narrow Focus, Critics Charge
Franklin Hoke | Jul 10, 1994 | 9 min read
Critics Charge Author: FRANKLIN HOKE, pp.1 Date: July 11,1994 Disputing what they see as unproductive preoccupation with HIV-specific studies, they step up campaign for a `wider window' of research Progress in AIDS research has faltered in the United States since the mid-1980s, according to some scientists, owing to a premature narrowing of the research focus by the scientific and administrative leadership of the National Inst

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