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image: Learning Opens the Genome

Learning Opens the Genome

By Ruth Williams | January 17, 2018

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

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The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment.


Researchers identify antibodies for two commonly used Cas9 proteins in human blood. Investors take notice.


image: Scientists Continue to Use Outdated Methods

Scientists Continue to Use Outdated Methods

By Catherine Offord | January 9, 2018

The use of underperforming computational tools is a major offender in science’s reproducibility crisis—and there’s growing momentum to avoid it.


image: Primary Cilia in Neurons Linked to Obesity

Primary Cilia in Neurons Linked to Obesity

By Abby Olena | January 8, 2018

Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 


image: Maternal Response to Zika Damages Mouse Fetuses

Maternal Response to Zika Damages Mouse Fetuses

By Catherine Offord | January 5, 2018

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

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image: Coriell Institute CEO Dies

Coriell Institute CEO Dies

By Kerry Grens | January 4, 2018

Michael Christman oversaw the organization’s well-known biobank and pioneered a personalized medicine initiative.


image: Alcohol Damages Mouse DNA

Alcohol Damages Mouse DNA

By Jef Akst | January 3, 2018

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.


The genome of an infant who lived in Alaska thousands of years ago represents a previously unknown group of humans called Ancient Beringians, who share a common lineage with other Native Americans. 


image: Child Receives Transgenic Skin

Child Receives Transgenic Skin

By Ruth Williams | January 1, 2018

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and resolved a dermatology debate to boot.


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