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tag immune rejection developmental biology immunology genetics genomics

3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
New Strategies to Discover Human Disease Genes
New Strategies to Discover Human Disease Genes
The Scientist | Oct 16, 2023 | 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
Illustration showing the upper part of a human body connected to a DNA helix
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD | Oct 31, 2023 | 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications. 
Red T cell
Jumping Genes Put a Target on Cancerous Cells
Natalia Mesa, PhD | Feb 14, 2023 | 4 min read
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
Microscopy image of the cnidarian <em>Hydractinia symbiolongicarpus&nbsp;</em>with cell nuclei stained blue and oocytes stained yellow
Ancient Immunoglobulin Genes Help Cnidarians Decide to Fight or Fuse
Sophie Fessl, PhD | Oct 11, 2022 | 4 min read
Immunoglobulin genes might have evolved much earlier than previously expected, perhaps even in the common ancestor of Cnidarians and Bilateria, a study suggests.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Immunology: Highlights From A Hot Biological Field
Scott Veggeberg | Mar 21, 1993 | 6 min read
Some of the most influential papers in 1992, according to data provided by the Philadelphia-based Institute for Scientific Information, were in immunology. This is not surprising, given the field's applications in stemming AIDS, cancer, and other pressing diseases. The most cited paper published within the last two years is from the Max Planck Institute for Biology in Tbingen, Germany (K. Falk, et al., Nature, 351:290, 1991). This paper, which by the end of February 1993 had been referred to i
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

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