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tag immune rejection evolution cell molecular biology genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Neanderthal DNA in Modern Human Genomes Is Not Silent
Jef Akst | Sep 1, 2019 | 10+ min read
From skin color to immunity, human biology is linked to our archaic ancestry.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
CRISPR, Cas-9, Nobel, Chemistry
CRISPR’s Adaptation to Genome Editing Earns Chemistry Nobel
Amanda Heidt | Oct 7, 2020 | 4 min read
Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.
Layered visual representation of multiomics
Integrate and Innovate with NGS and Multiomics
The Scientist and Illumina | May 4, 2023 | 6 min read
Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.
This shows a cryo-EM map of a Fanzor protein in complex with its guiding RNA (in purple) and DNA (target strand in red, complementary strand in blue).
CRISPR-like Abilities in Eukaryotic Proteins
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
Two groups independently discovered that Fanzor proteins in eukaryotic organisms are CRISPR’s genome-editing cousins.
close-up of X chromosomes
Probing “Selfish” Centromeres Unveils an Evolutionary Arms Race
Michael Lampson, PhD | Apr 3, 2023 | 10 min read
A more complete understanding of nonrandom segregation will shed light on how speciation occurs.

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