metabolomics

Microbiome studies have yielded hundreds of ideas for ways to detect and influence human health, but the field struggles with reproducibility challenges that hamper bringing these goals to fruition. Identical tubes of fecal matter should help.

Researchers redefine the lost art of smelling illness using one woman’s exquisitely sensitive nose.

A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.

The unique odor profiles of tumors can be used to develop diagnostic sensing tools.

Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness.

Researchers integrated information from 45 protein, metabolite, and immune data points to identify a window two to four weeks before a pregnant person will go into labor.

The gastrointestinal tracts of people with major depressive disorder harbor a signature composition of viruses, bacteria, and their metabolic products, according to the most comprehensive genomic and metabolomic analysis in depression to date.

The study of diet, long plagued by inaccuracies in self reports, is entering a new age of precision with the methods of metabolomics.

Nutrition researchers are beginning to use metabolomics to determine how healthy subjects’ diets are, and even to reveal specific properties of the foods they eat.

Whether it’s aligning software or prepping samples, researchers share their tips for studying the metabolome with this underused approach.

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.

Obesity-associated microbiome composition can persist after weight loss, affecting the exchange of metabolites between a mouse and its resident bugs, researchers report.