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image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By Abby Olena | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.

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Scientists are beginning to unravel the ways in which we develop a healthy relationship with the bugs in our bodies.

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image: Maternal Response to Zika Damages Mouse Fetuses

Maternal Response to Zika Damages Mouse Fetuses

By Catherine Offord | January 5, 2018

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

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image: Alcohol Damages Mouse DNA

Alcohol Damages Mouse DNA

By Jef Akst | January 3, 2018

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By Catherine Offord | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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image: Urine Test for TB Yields Results in 12 Hours

Urine Test for TB Yields Results in 12 Hours

By Jef Akst | December 14, 2017

The new test could improve upon two current methods to diagnose tuberculosis—a skin test or culturing bacteria from saliva, both of which take days.

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Water bears can reanimate after years of desiccation—and gel-forming proteins unique to the animals may explain how.

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image: Microbes of the Human Tongue Form Organized Clusters

Microbes of the Human Tongue Form Organized Clusters

By Kerry Grens | December 5, 2017

Bacteria on the tongue’s surface reside in clumps distinguished by genus, unlike the intermingled communities observed in other tissues.

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