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tag brown fat cell molecular biology

Treating Fat with Fat
Edyta Zielinska | May 1, 2012 | 7 min read
Is brown fat ready for therapeutic prime time?
Brain’s Role in Browning White Fat
Anna Azvolinsky | Jan 15, 2015 | 4 min read
Insulin and leptin act on specialized neurons in the mouse hypothalamus to promote conversion of white to beige fat.
Fat-busting protein
Tudor Toma(t.toma@ic.ac.uk) | Oct 3, 2001 | 1 min read
The protein 4E-BP1 converts white adipose tissue into brown adipose tissue and consequently reduces obesity.
The Skinny on Fat Cells
Anna Azvolinsky | Nov 1, 2015 | 8 min read
Bruce Spiegelman has spent his career at the forefront of adipocyte differentiation and metabolism.
Flipped Fat-burning Linked to Cancer Cachexia
Jyoti Madhusoodanan | Jul 22, 2014 | 2 min read
Conversion of white fat to brown is associated with muscle atrophy and weight loss in cancer patients.
Fat's Immune Sentinels
Justin Odegaard and Ajay Chawla | Dec 1, 2012 | 10 min read
Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.
The Skinny Fat
Bruce Spiegelman | Jan 1, 2008 | 8 min read
The Skinny Fat FRANKLYN RODGERS / SCIENCE PHOTO LIBRARY All Fat Cell images courtesy of Patrick Seale What if you could make fat cells burn energy rather than store it? By Bruce Spiegelman Related Articles Energy-burning baby fat Two paths for a preadipocyte From an outsider's perspective, obesity seems like a simple problem to solve: Eat less, exercise more. But, the body regulates food intake and feelings of satiety as part of a tightly regulated home
Investigating Molecular Motors Step by Step
Jeffrey Perkel | Mar 14, 2004 | 10+ min read
Thom Graves MediaThe audience, several hundred biophysicists strong, was not expecting a James Brown impersonation. But there he was: Physiologist Yale Goldman, keynote speaker on motility at the Biophysical Society's annual meeting, doing his "asymmetric hand-over-hand motility dance with a limp" to tinny strains of "Papa's Got a Brand New Bag." And while Goldman, who eschewed Brown's trademark, over-the-top couture for understated, Ivy League-issue khakis and blue blazer, won't star on MTV any
Week in Review: October 5–9
Tracy Vence | Oct 8, 2015 | 2 min read
This year’s Nobel Prizes; toward developing a brown fat-activating drug; certain antioxidants can increase the spread of melanoma in mice; anonymity and post-publication peer review
Flipping the Fat-Sensing Switch
Brendan Maher | Aug 18, 2002 | 6 min read
Image: Courtesy of David J. Mangelsdorf YIN AND YANG: Although they play opposite roles in bile acid production, these RXR heterodimers synergistically modulate cholesterol absorption and transport. When the molecular basis of Tangier disease was discovered in 1999,1 researchers lined up to study this orphan genetic disorder. Patients with Tangier have a propensity for heart disease and atherosclerosis, making this rare malady a model for some pressing health problems found in industrial

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