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tag brown fat genetics genomics

Photographic rendering of Woolly Mammoth and elephant with background elements merging together
Measuring Mammoth Mutations
Hannah Thomasy, PhD | Dec 1, 2023 | 2 min read
Comparing mammoth and elephant genomes revealed genetic mutations that may have helped mammoths survive in the Arctic.
A colorful mandarinfish on a reef
Genome Spotlight: Mandarinfish (Synchiropus splendidus)
Christie Wilcox, PhD | Oct 28, 2021 | 3 min read
The high-quality genome sequence sheds light on the colorful nature of these popular aquarium fish.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
A California Chinook Salmon Jumps into a waterfall during spawning season
Geneticists Light Up Debate on Salmon Conservation
Christie Wilcox, PhD | Feb 1, 2023 | 10+ min read
Splitting Chinook salmon into two groups based on their DNA could aid conservation efforts. But some researchers argue that this would be a misuse of the data.
The Skinny Fat
Bruce Spiegelman | Jan 1, 2008 | 8 min read
The Skinny Fat FRANKLYN RODGERS / SCIENCE PHOTO LIBRARY All Fat Cell images courtesy of Patrick Seale What if you could make fat cells burn energy rather than store it? By Bruce Spiegelman Related Articles Energy-burning baby fat Two paths for a preadipocyte From an outsider's perspective, obesity seems like a simple problem to solve: Eat less, exercise more. But, the body regulates food intake and feelings of satiety as part of a tightly regulated home
Flipping the Fat-Sensing Switch
Brendan Maher | Aug 18, 2002 | 6 min read
Image: Courtesy of David J. Mangelsdorf YIN AND YANG: Although they play opposite roles in bile acid production, these RXR heterodimers synergistically modulate cholesterol absorption and transport. When the molecular basis of Tangier disease was discovered in 1999,1 researchers lined up to study this orphan genetic disorder. Patients with Tangier have a propensity for heart disease and atherosclerosis, making this rare malady a model for some pressing health problems found in industrial
a polar bear with its head resting on its paws
The Polar Bear’s Prehistoric Past
Ed Yong | Jul 23, 2012 | 4 min read
Genomic analyses reveal that the polar bear evolved between 4 and 5 million years ago, far earlier than previous studies had estimated.
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
Bacteria and Humans Have Been Swapping DNA for Millennia
Kelly Robinson and Julie Dunning Hotopp | Oct 1, 2016 | 8 min read
Bacteria inhabit most tissues in the human body, and genes from some of these microbes have made their way to the human genome. Could this genetic transfer contribute to diseases such as cancer?
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat

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