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tag alternative splicing evolution microbiology

Alternative Splicing Goes Mainstream
Sam Jaffe | Dec 14, 2003 | 10 min read
In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly 30,000-gene genome to produce the dizzying variety of proteins that some believe is necessary to produce beings as complex as humans. Alternative splicing--the post-transcriptional editing process that can result in various mRNAs--was previously seen as an interesting but relatively uncommon sidesh
Cancer’s Escape Routes
Tia Ghose | Nov 29, 2011 | 5 min read
Scientists are beginning to discover myriad strategies tumors use to avoid attacks by anti-cancer drugs.
Pufferfish Genomes Probe Human Genes
Ricki Lewis | Mar 17, 2002 | 7 min read
It may be humbling to think that humans have much in common with pufferfish, but at the genome level, the two are practically kissing cousins. "In terms of gene complement, we are at least 90% similar—probably higher. There are big differences in gene expression levels and alternate transcripts, but if you're talking about diversity, number and types of proteins, then it's pretty difficult to tell us apart," says Greg Elgar, group leader of the Fugu genome project at the Medical Research C
Genome Economy
Ricki Lewis | Jun 10, 2001 | 10 min read
The Human Genome Project's discovery1 that the human body runs on an instruction manual of a mere 35,000 or so genes--compared to the worm's 19,000, the fruit fly's 13,000, and the tiny mustard relative Arabidopsis thaliana's 25,000--placed humanity on an even playing field with these other, supposedly simpler, organisms. It was a humbling experience, but humility quickly gave way to awe with the realization that the human genome might encode 100,000 to 200,000 proteins. Scientists base this num
Radioimmunoassay: A Proven Performer In the Bio Lab
Rebecca Krumm | May 15, 1994 | 9 min read
AUTHOR: REBECCA KRUMM, pp.17 Date: May 16,1994 SUPPLIERS OF RADIOIMMUNOASSAY KITS, REAGENTS, AND SUPPLIES The following companies offer radioimmunoassay supplies and equipment. Please contact the companies directly for more information concerning specific products. Advanced Chemtech 5609 Fern Valley Rd. Louisville, Ky. 40228 (502) 969-0000 Fax: (502) 968-1000 AMAC Inc. 160B Larrabee Rd. Westbrook, Maine 04092 (207) 854-0426 Fax
Radioimmunoassay: A Proven Performer In the Bio Lab
Rebecca Krumm | May 15, 1994 | 9 min read
AUTHOR: REBECCA KRUMM, pp.17 Date: May 16,1994 SUPPLIERS OF RADIOIMMUNOASSAY KITS, REAGENTS, AND SUPPLIES The following companies offer radioimmunoassay supplies and equipment. Please contact the companies directly for more information concerning specific products. Advanced Chemtech 5609 Fern Valley Rd. Louisville, Ky. 40228 (502) 969-0000 Fax: (502) 968-1000 AMAC Inc. 160B Larrabee Rd. Westbrook, Maine 04092 (207) 854-0426 Fax
Forthcoming Books
The Scientist Staff | Jun 14, 1987 | 4 min read
This list of forthcoming books has been compiled from the latest information available from publishers. Dates of publication, prices and numbers of pages are tentative, however, and are subject to change. Astronomy The Classification of Stars. Carlos Jaschek and Mercedes Jaschek. Cambridge University Press: July, 432 pp, $79.50. A comprehensive handbook on the tools and results of stellar taxonomy, describing modern methods of spectroscopic and photometric classification. The Cosmos from Space.
One Link Found, Many to Go; The Rat's Now in the Ring; Red River for a Red Planet
Josh Roberts | May 18, 2003 | 4 min read
One Link Found, Many To Go Researchers at the UK's Cambridge Institute of Medical Research (CIMR) and Merck & Co. reported a link between cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and autoimmunity (H. Ueda et al., "Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease," Nature, e-pub ahead of print, doi:10.1038/nature01621, April 30, 2003). The researchers used positional cloning to search a 330 kb region surrounding the CTLA4 gene for polymorp
Deviations From The Norm: Systems For Mutation Detection Reveal Hidden Potentials
Kailash Gupta | Jul 18, 1999 | 10+ min read
Date: July 19, 1999Mutation Detection Systems and Methods Affymetrix's p53 chip Researchers leading the Human Genome Project (HGP) originally envisioned completion of the entire genome sequence (approximately 3 billion base pairs) by the year 2005. Recently the arena of human genome sequencing has seen a lot of heat generated by the entry of both commercial entrepreneurs and public consortia. Celera, a company formed by highly skilled and competent commercial organizations (TIGR and Perkin-Elm
GM Crops Face Heat Of Debate
Ricki Lewis | Oct 10, 1999 | 10+ min read
For a successful technologyReality must take precedence over public relations, for nature cannot be fooled. --Richard Feynman Nobel physicist Richard Feynman was talking about the role NASA and its industrial partners played in the 1986 Challenger disaster, but his words could easily apply to the debate over genetically modified (GM) crops. When grain processor Archer Daniels Midland (ADM) of Decatur, Ill., asked suppliers on Sept. 2 to segregate GM corn from traditional varieties, some U.S. b

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