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tag scientific ethics microbiology disease medicine genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
cartoon showing a hand taking a tool to a double-helix of DNA to represent gene editing
WHO Releases New Recommendations on Human Genome Editing
Annie Melchor | Jul 12, 2021 | 3 min read
The guidance comes after two years of consulting with hundreds of stakeholders, including indigenous peoples, religious leaders, patient groups, and scientists.
Matthieu Groussin sits with three other people on stools in front of a low table, on which there are several bowls of food. Another person stands above Groussin spooning something into a bowl.
Q&A: Gathering Diverse Microbiome Samples
Katherine Irving | Nov 3, 2022 | 8 min read
Cofounders of a microbiome biobank speak with The Scientist about their new partnership with nonprofit OpenBiome and how to ethically work with donors.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Illustration of scientists collaborating
How to Bring the Public into the Scientific Process
Amanda Heidt | Mar 14, 2022 | 10+ min read
A new wave of research is recruiting patients and other members of the public to serve as equal partners, bringing fresh perspectives to research on diseases and other conditions.
Scientific, Ethical Questions Temper Pharmacogenetics
Karen Young Kreeger | Jun 10, 2001 | 6 min read
The field of pharmacogenetics, the study of inherited differences that influence a person's response to drugs, rivals bioinformatics in claims about how it will revolutionize pharmaceutical research. To be sure, pharmacogenetics and its allied discipline, pharmacogenomics (the use of tools such as microarrays and proteomics to study drug response) has opened a wealth of research questions and job opportunities. But scientists are still working to untangle the ethical and research complications t
US Senators Call for International Guidelines for Germline Editing
Jef Akst | Jul 16, 2019 | 2 min read
In the wake of reports of CRISPRed babies born in China, a bipartisan resolution “opposes the experiments that resulted in pregnancies using genome-edited human embryos.”

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