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tag mouse model disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
The Scientist Staff | Mar 28, 2024
3D illustration of damaged myelin sheath seen in demyelinating diseases such as multiple sclerosis.
Tracking Down Innate Immune Cells in Multiple Sclerosis
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 5 min read
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
Orange colony of bacteria on red medium
Skin Bacteria May Trigger Lupus: Mouse Study
Natalia Mesa, PhD | Oct 28, 2022 | 3 min read
Staphylococcus aureus appears to be the culprit.
Zebrafish with fluorescent nervous system in green.
Oust the Mouse: A Plan to Reduce Mammal Use in Drug Development
Natalia Mesa, PhD | Mar 15, 2022 | 7 min read
The Scientist spoke to Mount Desert Island Biological Laboratory’s Jim Strickland about the institute’s new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models.
New Zika Mouse Model
Tanya Lewis | Apr 5, 2016 | 2 min read
Researchers develop another mouse model of Zika virus infection that mimics the disease in humans.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
You Are When You Eat
Iris Kulbatski, PhD | Nov 20, 2023 | 3 min read
Intermittent fasting regulates biological time and improves disrupted sleep in an Alzheimer’s disease model.
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Engineered Yeast Robots Destroy Inflammatory Molecules in an IBD Mouse Model
Roni Dengler, PhD | Aug 16, 2021 | 3 min read
Scientists added a gene circuit that senses and neutralizes proinflammatory ATP to yeast, taking another step towards precision medicine.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

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