A guide to DNA-encoded libraries for drug discovery

Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.

A handful of new studies moves the needle toward a consensus on the long-disputed question of whether insect wings evolved from legs or from the body wall, but the devil is in the details.

A parasitic worm accumulates epigenetic DNA tags over its lifetime.  

Also known as superworms, the scavengers are able to digest the plastic, opening up the possibility of harnessing their abilities to help tackle our pollution crisis.

A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research.

Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.

The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.

A T cell discovery, “hachimoji” DNA, a new species of human, and mounting fears of espionage rounded off the list this year.

By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo