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Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
drug delivery, disease & medicine
Bacteria as Living Microrobots to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 10+ min read
Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.
Laser-Triggered Nanobubbles Blast a Path into Biofilms
Jonathan Wosen | Apr 1, 2020 | 4 min read
Researchers could one day use the method to deliver antibiotics to topical wounds infected by hard-to-treat masses of bacteria.
Trial of Gene Therapy for Duchenne Muscular Dystrophy Put on Hold
Catherine Offord | Nov 12, 2019 | 2 min read
The US Food and Drug Administration halts a study by Solid Biosciences after a patient experiences severe side effects following treatment.
Image of the Day: Smartphone-Controlled Brains
Nicoletta Lanese | Aug 7, 2019 | 1 min read
A device implanted into mice can modulate brain circuit activity over long periods of time.
Image of the Day: Artificial Snake Bite
Nicoletta Lanese | Aug 6, 2019 | 1 min read
A microneedle delivers liquid medicines through tiny, fang-like points.
Image of the Day: Right on Target
Nicoletta Lanese | Jul 23, 2019 | 1 min read
An injectable biomaterial calls cancer drugs to tumor sites in mice.