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tag drug delivery ecology neuroscience

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Antidepressant Approvals Could Herald New Era in Psychiatric Drugs
Bianca Nogrady | Oct 1, 2019 | 9 min read
The FDA has given the green light to the first major new classes of antidepressant therapies in decades, opening up new avenues for therapeutic development.
Using Temperature-Sensitive Channels to Study Neural Circuitry
Devika G. Bansal | Nov 1, 2018 | 8 min read
Meet the researchers building a thermogenetic toolbox.
Chemyx: Tracing Fibers - From DiI to Modern Methods
Chemyx Inc. | Apr 24, 2018 | 3 min read
Visualizing neuronal connections is highly important for understanding brain organization and pathophysiology. However, this data has historically been obtained through invasive and often terminal procedures. Technological advances have permitted the development of a new era of neuroanatomical tracing techniques.   
Behavior in Action
Kelly Rae Chi | Oct 1, 2009 | 7 min read
By Kelly Rae Chi Behavior in Action Tools and techniques for tracking mammalian behavior. Even the seemingly simplest mammalian behaviors, such as grooming one’s offspring, involve a complex series of tiny movements that may be invisible to the human eye. But in studying those behaviors, how to break them down into reliable, measurable components? “All of these advances in technology give us data that [weren’t] available
The Four R's
Amy Norton | Nov 21, 2004 | 7 min read
Teams at each of New York City's leading universities are making important research advances.
Underground Supermodels
Thomas J. Park and Rochelle Buffenstein | Jun 1, 2012 | 10+ min read
What can a twentysomething naked mole-rat tell us about fighting pain, cancer, and aging?
Creative Expression: Mammalian Expression Vectors and Systems
Christopher Smith | Feb 1, 1998 | 7 min read
Date: February 2, 1998 Chart 1 Chart 2 Prokaryotic expression systems, reviewed in the September 1, 1997, issue of The Scientist were part of the early repertoire of research tools in molecular biology. Although the expression of recombinant protein in prokaryotes provided a means to develop other research tools (antibodies, for example ) and study basic aspects of biological function, the scope and depth of this research were limited, especially with regard to eukaryotic proteins. The de novo
Assays by the Score
Deborah Fitzgerald | May 27, 2001 | 9 min read
Click to view the PDF file: Bead-based Fluorescent Multiplex Protein Analysis Systems Courtesy of LINCO ResearchLabMAP-based systems use internally dyed fluorescent microspheres to analyze as many as 100 different analytes concurrently. Today's competitive, high-paced research environment has stimulated the development of a host of approaches for rapid, cost-efficient analyses of large numbers of samples. In keeping with this trend, methods for simultaneously analyzing multiple species in a g

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