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tag radioactive pollution developmental biology

Beyond Film: Laboratory Imagers
Jorge Cortese | Apr 1, 2002 | 9 min read
Years ago, researchers had only one data-imaging option: autoradiography. These scientists tagged samples—whether nucleic acid, protein, cell, or tissue—with radioactive labels, and captured images on film. Safety concerns, convenience, and sensitivity, spurred the development of alternative techniques, and today, researchers can choose from a range of options, including fluorescence, chemifluorescence, and chemiluminescence, in addition to autoradiography. Fluorescence occurs when
Immunoassay Techniques Proven To Be Outstanding In Several Fields
Holly Ahern | Oct 1, 1995 | 10 min read
SIDEBAR: Selected Suppliers of Immunoassays and Assay Systems Immunoassays combine principles of immunology and chemistry into tests that are used by scientists in practically every discipline, including fields as diverse as molecular biology and environmental science. In research applications, immunoassays such as immunoblotting (detecting membrane-bound proteins), immunohistochemistry (cell or tissue staining), and enzyme immunoassays provide a sensitive and specific means of detecting targe
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
Assessing Differential Gene Expression
Barbara Cunningham | Nov 25, 2001 | 9 min read
As the complete human genome sequence emerges, research shifts from questions of genomics to those of proteomics--determining the function of individual gene products and mapping global gene expression patterns. Gene expression patterns change continually during the course of tissue development and differentiation. The expression of different gene products at any given time within a particular cell defines the cell's characteristics and helps determine how it will react to external stimuli. Alte
Blotting Technology's Permanence Is Assured As Its Applications In The Laboratory Flourish
Holly Ahern | Nov 27, 1994 | 10 min read
Advanced Biotechnologies Inc. Columbia, MD Advanced Genetic Technologies Corp San Diego, CA Ahlstrom Filtration Inc. Mount Holly Springs, PA American Bioanalytical Inc. Natick, MA Boehringer Mannheim Corp. Indianapolis, IN P.J. Cobert Associates St. Louis, MO Crescent Chemical Inc. Hauppauge, NY DuPont NEN Boston, MA Fluka Chemical Corp. Ronkonkoma, NY Gallard-Schlesinger Industries Inc. Carle Place, NY Hoefer Scientific
Blotting Technology's Permanence Is Assured As Its Applications In The Laboratory Flourish
Holly Ahern | Nov 27, 1994 | 10 min read
Advanced Biotechnologies Inc. Columbia, MD Advanced Genetic Technologies Corp San Diego, CA Ahlstrom Filtration Inc. Mount Holly Springs, PA American Bioanalytical Inc. Natick, MA Boehringer Mannheim Corp. Indianapolis, IN P.J. Cobert Associates St. Louis, MO Crescent Chemical Inc. Hauppauge, NY DuPont NEN Boston, MA Fluka Chemical Corp. Ronkonkoma, NY Gallard-Schlesinger Industries Inc. Carle Place, NY Hoefer Scientific
Pursuing Proteomes
Deborah Wilkinson | Jun 11, 2000 | 9 min read
Bio-Rad's PROTEAN® IEF System provides 2-D electrophoretic separation as part of the ProteomeWorks System Australian postdoctoral fellow Marc Wilkins coined the term "proteome" in the mid-'90s, referring to the total set of proteins expressed in a given cell at a given time. The term took hold, and a new scientific discipline was born. In proteomic studies, all the proteins from a given cell, organelle, or tissue are analyzed simultaneously with respect to properties such as expression leve
One Step Beyond: Going Beyond Genomics With Proteomics And Two-Dimensional Gel Technology
Laura Defrancesco | Jan 3, 1999 | 10+ min read
Proteomes and 2D Gel Apparatus Providers Big science has moved on to proteins. With the new brand of science termed proteomics--named by the Australians Marc Wilkins and Keith Williams to mean the "set of PROTEins encoded by the genOME"--the push is on around the globe to produce a complete description of a cell/tissue/organism in terms of the proteins produced. The challenge is all the greater because the expressed protein pattern changes with time and environment--responding to developmenta
Antibodies Making Their Way From The Clinic To The Research Lab
Holly Ahern | Sep 17, 1995 | 10 min read
if (n == null) The Scientist - The Immune Response The Scientist 9[18]:18, Sep. 18, 1995 Tools The Immune Response By Holly Ahern Imagine that you've just cloned a gene for a bacterial enzyme with unique structural properties and you want to find out more about it. What natural role does the enzyme play, you wonder, and do organisms other than bacteria produce it? To answer these questions, you could screen countless genomic libraries for clones bearing si

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