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Mice who get less attention from their mothers have more copies of a common retrotransposon in the genomes of their hippocampal neurons.

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image: Infographic: Understanding Our Diverse Brain

Infographic: Understanding Our Diverse Brain

By Sara B. Linker, Tracy A. Bedrosian, and Fred H. Gage | November 1, 2017

Recent advances in single-cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.

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image: Advancing Techniques Reveal the Brain’s Impressive Diversity

Advancing Techniques Reveal the Brain’s Impressive Diversity

By Sara B. Linker, Tracy A. Bedrosian, and Fred H. Gage | November 1, 2017

No two neurons are alike. What does that mean for brain function?

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image: RNA Protects “Naked” Genomes from Retrotransposons

RNA Protects “Naked” Genomes from Retrotransposons

By Shawna Williams | June 30, 2017

Transfer RNA fragments prevent jumping genes from hopping around in the mouse embryo, when histone methylation can’t do the job.

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image: Sequencing Reveals Genomic Diversity of the Human Brain

Sequencing Reveals Genomic Diversity of the Human Brain

By Ben Andrew Henry | September 16, 2016

Researchers examine the role of long interspersed element-1 retrotransposition in neuronal mosaicism.

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From sequencing bacteriophages to synthesizing bacterial genomes to defining a minimal genome

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image: Tethering Transposons

Tethering Transposons

By Ruth Williams | October 15, 2015

Panoramix, a newly identified transcription repressor, takes the bounce out of jumping genes.

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image: Wrangling Retrotransposons

Wrangling Retrotransposons

By Michael Van Meter, Andrei Seluanov, and Vera Gorbunova | March 1, 2015

These mobile genetic elements can wreak havoc on the genome. Researchers are now trying to understand how such activity contributes to the aging process.

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image: Schizophrenia’s Jumping Genetics

Schizophrenia’s Jumping Genetics

By Jef Akst | January 6, 2014

Researchers find evidence that transposable elements, also known as jumping genes, may contribute to the development of the psychiatric disorder.

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image: DNA Jumps Between Vertebrates

DNA Jumps Between Vertebrates

By Dan Cossins | January 3, 2013

Scientists show that horizontal transfer of a particular DNA sequence among a diverse range of vertebrates is more widespread than previously believed.

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