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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By Amanda B. Keener | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.


Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

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image: <em>Oncotarget</em> Journal Cut from Medline

Oncotarget Journal Cut from Medline

By Katarina Zimmer | October 26, 2017

New papers from a cancer journal once named as a possibly predatory publication will no longer appear in the widely used research database.


With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: Image of the Day: Fragile Brain

Image of the Day: Fragile Brain

By The Scientist Staff | October 3, 2017

In Fragile X syndrome—a genetic mishap that results in cognitive delays—the lack of a translation-repressing protein leads to the rampant accumulation of other proteins in the mouse brain.


image: Damage Patroller

Damage Patroller

By Anna Azvolinsky | October 1, 2017

Stephen Elledge has built a career studying how eukaryotic cells maintain genomic integrity.


The 38-year-old synthetic biologist comes from a long line of tinkerers and engineers.


image: Live Cell Extractions

Live Cell Extractions

By Ruth Williams | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By Shawna Williams | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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Pauses may help cells fine-tune gene expression.


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