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The discovery suggests that the immune checkpoint can operate at a further distance from tumor cells than previously believed.

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image: Immune Checkpoint Found Lacking in Type 1 Diabetes

Immune Checkpoint Found Lacking in Type 1 Diabetes

By Ruth Williams | November 15, 2017

Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.

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image: An Immunological Timeline for Pregnancy

An Immunological Timeline for Pregnancy

By Catherine Offord | September 1, 2017

A new study uses blood samples from pregnant women to track changes in the immune system leading up to birth, and predicts gestational age from the mothers’ immune signatures.

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image: Inhibiting Sperm Protein Causes Infertility

Inhibiting Sperm Protein Causes Infertility

By Karen Zusi | October 5, 2015

Two drugs targeting a protein in sperm cause reversible infertility in male mice, providing new hope for a male contraceptive.

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image: Done with Immunosuppressants

Done with Immunosuppressants

By Jef Akst | July 3, 2014

Adult sickle-cell patients have safely stopped taking their immunosuppressant medication thanks to a new type of blood stem-cell transplant.

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image: T cells and Transplantation

T cells and Transplantation

By Ruth Williams | November 13, 2013

Drug-resistant immune cells protect patients from graft-versus-host disease after bone marrow transplant.

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image: Transplant Without Drugs?

Transplant Without Drugs?

By Edyta Zielinska | March 8, 2012

A new method for transplanting immunologically mismatched organs may remove the need for life-long immunosuppressive drugs to prevent rejection.

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