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tag contamination evolution cell molecular biology

A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
Cross-Sample Sequencing Contamination Galore
Ruth Williams | Apr 5, 2017 | 3 min read
Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Millipore stock
Viral Nucleic Acid Purification in a Single Spin
The Scientist and MilliporeSigma | Apr 6, 2022 | 3 min read
A simple nucleic acid extraction approach quickly purifies genomic viral RNA and DNA while minimizing cross-contamination risks.
Tag! Purifying Proteins with Affinity Chromatography
Aileen Constans(aconstans@the-scientist.com) | Feb 27, 2005 | 6 min read
What is now a standard protein laboratory technique began as an act of desperation.
scanning electron microscope image of clawlike microscopic organisms on a smoother surface
Phyla of Tiny Filter Feeders Find a New Spot on the Tree of Life
Alejandra Manjarrez, PhD | Jul 6, 2022 | 5 min read
A new study using fairly complete genetic datasets of two phyla of small suspension feeders (Ectoprocta and Entoprocta) reopens the debate on the phylogenetic relationships between them and other animals.
Landscape illustration
Horizontal Gene Transfer Happens More Often Than Anyone Thought
Christie Wilcox, PhD | Jul 5, 2022 | 10+ min read
DNA passed to and from all kinds of organisms, even across kingdoms, has helped shape the tree of life, to a large and undisputed degree in microbes and also unexpectedly in multicellular fungi, plants, and animals.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.

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