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Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Week in Review, June 17–21
Jef Akst | Jun 21, 2013 | 4 min read
On the gene patent decision; a high-res human brain model; bats’ influence on moths mating calls; toxicants threaten brain health; platelet-driven immunity
Assays Galore
Lanette Fee | Sep 21, 2003 | 9 min read
Courtesy of BD Biosciences Pharmingen  COLOR CODING: Multiplexed bead-based assays, like BD Biosciences' Cytometric Bead Array (shown), test for multiple analytes in a single vial. The key is in the colors: one hue indicates the bead ID, and the intensity of the second, how much protein has been captured. In today's fast-paced research environment, technologies for speedy, cost-efficient analyses reign supreme. As part of this general trend, techniques for multiplexing, that is, simultan
antibiotics antibiotics resistance persister bacteria bacteriophage
Opinion: We Need More than New Antibiotics to Fight Resistance
Neil S. Greenspan and Arturo Casadevall | Nov 1, 2019 | 3 min read
Metabolic disrupters, phages, and other approaches are going to be needed to treat the broadest possible range of patients infected by bacterial pathogens resistant to multiple drugs.
One Colombian's Quest For A Malaria Vaccine
John Lauerman | Dec 25, 1988 | 9 min read
In March of this year, Colombia heard some important news that had nothing to do with the country’s infamous drug trade. A Colombian scientist named Manuel E. Patarroyo published a study in Nature showing that an experimental vaccine he had developed was tantalizingly effective against malaria, a disease that threatens two-thirds of the world’s population. Until then, the parasite that causes malaria had stubbornly resisted the efforts of hundreds of researchers in the U.S. and Eur
Biotech Faces Evolving Patent System
Douglas Steinberg | Mar 5, 2000 | 8 min read
Like medieval alchemists, modern biologists apply intricate, esoteric protocols to lowly matter, such as bacteria and rodents. Unlike alchemists, biologists successfully transmute these creatures into gold--disease-fighting pharmaceuticals and profits accruing from them. An indispensable ingredient in this dross-to-drug process is patent protection, which preserves monopoly and attracts investment. Unfortunately, the patent system isn't as ideal a catalyst as the chimerical philosopher's stone s
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
The Biggest Stories in Bioscience 2005
Ishani Ganguli | Dec 4, 2005 | 8 min read
Life scientists have been challenged more than ever this year not just to critically analyze data, but to better interpret those data for an increasingly critical public.
Notebook
The Scientist Staff | Apr 26, 1998 | 8 min read
WHAT FOLLOWS TAMOXIFEN? Warnings accompanied recent announcements from the University of Pittsburgh-based National Surgical Adjuvant Breast and Bowel Project and the National Cancer Institute in Bethesda, Md., that tamoxifen achieved a 45 percent reduction in the incidence of breast cancer compared to women who took a placebo in the Breast Cancer Prevention Trial. The 25-year-old drug still carries the risk of serious side effects for women over 50, officials said. But the overall results were
Notebook
The Scientist Staff | Sep 14, 1997 | 8 min read
Table of Contents Fisher Case Is Settled Loaded Questions Malaria Immunity Scientific Immigration Slips Terminating Telomerase Getting Tough With E.Coli Hospitable Merger `No Confidence' Vote For Confide Mendel's Mighty Midgets Bullish on Cloning Research 'A VICTORY': Bernard Fisher accepted a favorable settlement in a long-running dispute with the government and the University of Pittsburgh. Showered with praise, apology, and a financial settlement, cancer surgeon Bernard Fisher has triump

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