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Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Do Patents Promote or Stall Innovation?
Catherine Offord | Jun 1, 2016 | 10 min read
A petition recently filed with the Supreme Court triggers renewed debate about the role of patents in the diagnostics sector.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
The Scientist Staff | Mar 28, 2024
Bioterrorism Research: New Money, New Anxieties
John Dudley Miller | Apr 6, 2003 | 8 min read
Ned Shaw US scientists have reason to feel both heady and scared. The federal government recently released unprecedented billions of dollars to fund bioterrorism research. Yet, the merits of this sudden shift in focus are being debated, and some worry that the money will be squandered or wasted. "I have been really very upset by the focus on bioterrorism," says Stanley Falkow, professor of microbiology and immunology and of medicine at Stanford University. "Everybody's talking about it, but th
Software Helps Researchers In Sorting Through The Human Genome
Ricki Lewis | Jul 21, 1996 | 10 min read
The Human Genome SIDEBAR : Selected Suppliers of Software for Gene Discovery and Analysis Genetics has been an informational science since the elucidation of DNA's structure. Today's researchers say the field shifted to a more computational mode in 1990-the year that research groups began mapping genes to specific chromosomal sites for the Human Genome Project. "That year was pivotal, because it was then that the need to sequence significant amounts of DNA became compelling," says Richard Gib
Notebook
The Scientist Staff | Mar 30, 1997 | 7 min read
The American Medical Association (AMA), not to be outdone by the recent controversies surrounding sheep cloning, wrestled with a few ethical issues of its own earlier this month in Philadelphia. At a conference entitled "Ethics and American Medicine: History, Change, and Challenge," speakers tackled subjects such as end-of-life care and the problems of managed care and health-care rationing. The meeting’s concluding session, a roundtable discussion on medicine’s future ethical chall
Biotech Faces Evolving Patent System
Douglas Steinberg | Mar 5, 2000 | 8 min read
Like medieval alchemists, modern biologists apply intricate, esoteric protocols to lowly matter, such as bacteria and rodents. Unlike alchemists, biologists successfully transmute these creatures into gold--disease-fighting pharmaceuticals and profits accruing from them. An indispensable ingredient in this dross-to-drug process is patent protection, which preserves monopoly and attracts investment. Unfortunately, the patent system isn't as ideal a catalyst as the chimerical philosopher's stone s
The Biggest Stories in Bioscience 2005
Ishani Ganguli | Dec 4, 2005 | 8 min read
Life scientists have been challenged more than ever this year not just to critically analyze data, but to better interpret those data for an increasingly critical public.

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