gut microbiota

Two new techniques allow researchers to manipulate the activity of gut bacteria. 

Individuals who are more social and report feeling close with their families display similar gut microbes. 

Corbiculate bees and their gut-dwelling microbes have been coevolving since the social species evolved from their solitary ancestors around 80 million years ago, scientists suggest. 

SP140, an epigenetic reader protein mutated in a number of autoimmune disorders, is essential for macrophage function and preventing intestinal inflammation, scientists show. 

Fecal transplants from humans with irritable bowel syndrome and anxiety into mice lead to similar symptoms and anxiety-like behavior in the rodents, researchers report.  

Byproducts of gut microbes in some 1-month–old babies trigger inflammation that is linked to later asthma development, researchers find.

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

Three therapeutic doses administered during early life disturb the animals’ microbiomes and lead to enduring changes in the immune systems of non-obese diabetic mice, researchers report.

Seres Therapeutics’s microbiome-targeting therapy for recurrent Clostridium difficile infection fails a Phase 2 clinical trial.

Symbiotic gut bacteria evolved and diverged along with ape and human lineages, researchers find. 

A bidirectional link between the brain and the gut can improve or worsen brain injury in mice, researchers report.

Analyzing the gut microbiomes of children from birth through toddlerhood, researchers tie compositional changes to birth mode, infant diet, and antibiotic therapy.

Changes in diet can cause gut microbes to produce acetate, which in turn stimulates insulin secretion and obesity in rodents, scientists show.

Post-publication peer review prompts the authors to clarify the ages of mice used in their experiments and share additional data.

Contrary to the popular thought that many species are “unculturable,” the majority of bacteria known to populate the human gut can be grown in the lab, scientists show.

Donor bacteria coexist with a recipient’s own for three months after a fecal transplant.

Parasitic worms promote the growth of beneficial intestinal microbes in a mouse model of inflammatory bowel disease.

Understanding cancer’s relationship with the human microbiome could transform immune-modulating therapies.

In recent years, research has demonstrated that microbes living in and on the mammalian body can affect cancer risk, as well as responses to cancer treatment.

Fecal matter transplants may transfer nonpathogenic viruses along with beneficial bacteria, scientists show.