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tag bacterial toxin cell molecular biology immunology culture

Host Cells Release Exosomes to Sop Up Bacterial Toxins
Rachael Moeller Gorman | Jun 1, 2020 | 3 min read
During bacterial infection, autophagy proteins appear to regulate the release of cell-saving exosomes, which bear the brunt of toxin damage.
T Cells That Drive Toxic Shock in Mice Identified
Ashley Yeager | Jun 20, 2017 | 3 min read
Overzealous activity by mucosa-associated invariant T (MAIT) cells in response to bacterial toxins can lead to illness instead of stopping it.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Postmodern Culture: Maximizing Cell Culture Output At Every Level
Grant Meisenholder | Jul 4, 1999 | 10 min read
Date: July 5, 1999Products for High-Volume Tissue Culture The Automation Partnership's CELLMATETM Automated Cell Culture Processing System Mammalian cell culture has finally come into its own as a way to produce cells, proteins, or sub-cellular components in large scale. Recent advances in cell culture systems are allowing scientists to better circumvent problems associated with bacterial systems such as incomplete protein expression, toxin contamination, and incompatibility. Today's wide arra
A computer-generated graphic showing a cross-section of red-colored bacteria, with the locations of the protein APOL3 labeled in green.
Human Protein Dissolves Bacterial Membranes
Abby Olena, PhD | Jul 15, 2021 | 4 min read
The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
The Vaginal Microbiome is Finally Getting Recognized
Hannah Thomasy, PhD, Drug Discovery News | Sep 25, 2023 | 10+ min read
Vaginal dysbiosis has long been a taboo subject, but studying and optimizing the vaginal microbiome could be a game changer for women's health.
Black and gold sketch of Katalin Karikó and Drew Weissman.
Nobel Prize for mRNA Vaccines
Danielle Gerhard, PhD | Oct 2, 2023 | 5 min read
Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines.

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