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image: Image of the Day: Mouse Pupil

Image of the Day: Mouse Pupil

By The Scientist Staff | January 19, 2018

Pupil constriction during sleep may protect the murine brain from being awakened by sudden flashes of light.

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image: Image of the Day: Muscle Bouquet 

Image of the Day: Muscle Bouquet 

By The Scientist Staff | January 16, 2018

Lab-grown muscle stem cells from mice mimic the formation of muscle fibers in vivo. 

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image: A Database of Genetic Differences Among Lab Mice

A Database of Genetic Differences Among Lab Mice

By Ashley P. Taylor | August 7, 2017

Researchers have catalogued mutations in the coding regions of 36 of the most important mouse strains.

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The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  

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Discrepancies in the populations’ immune systems suggest murine models of immunological disorders possess more limitations than scientists had appreciated.

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image: Why Obese Mice Prefer To Sit Around All Day

Why Obese Mice Prefer To Sit Around All Day

By Joshua A. Krisch | January 3, 2017

A study links excess body weight in the rodents with dopamine receptor inactivity and reduced movement.

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image: Study: Enriched Housing Changes Murine T Cells

Study: Enriched Housing Changes Murine T Cells

By Jef Akst | October 3, 2016

Mice that live in a more-stimulating environment for two weeks appear to develop a more-inflammatory immune state that might help protect the animals against infection. 

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image: Immune Defect Detected in Knockout Mice

Immune Defect Detected in Knockout Mice

By Tanya Lewis | May 20, 2016

Researchers have identified a mutation in a commonly used commercial mouse strain that could impact experimental results.

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image: Drug Spurs Digestion

Drug Spurs Digestion

By Jef Akst | January 6, 2015

A new drug shows promise as a weight-loss solution in mice, prompting the animals to burn calories in the absence of a meal.

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image: May the Best Rodent Win

May the Best Rodent Win

By Molly Sharlach | January 1, 2015

Are mice, considered by some to be the less intelligent rodent, edging out rats as laboratory models of decision making?

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