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image: A Radical Intervention, 1894

A Radical Intervention, 1894

By Catherine Offord | April 1, 2018

William Halsted’s approach to mastectomy took the medical world by storm at the turn of the last century.

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Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

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image: Cancer Evolutionist: A Profile of Charles Swanton

Cancer Evolutionist: A Profile of Charles Swanton

By Anna Azvolinsky | April 1, 2018

Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.

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image: Caught on Camera

Caught on Camera

By The Scientist Staff | April 1, 2018

Selected Images of the Day from the-scientist.com

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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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image: Contributors

Contributors

By The Scientist Staff | April 1, 2018

Meet some of the people featured in the April 2018 issue of The Scientist.

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A new device uses anchored nanowires to capture extracellular vesicles from pee for microRNA analysis.

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Mutations in the TP53 gene appear to influence the prognosis and likelihood of future cancers in pediatric leukemia patients.

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image: Metastatic Knowledge

Metastatic Knowledge

By Bob Grant | April 1, 2018

The research enterprise surrounding cancer spreads and changes as it explores multiple facets of the complex disease.

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image: Mutant RAS Proteins Team Up for Oncogenicity

Mutant RAS Proteins Team Up for Oncogenicity

By Jim Daley | April 1, 2018

Mice with cancer whose KRAS proteins couldn’t link together had much better survival outcomes than those whose oncogenic mutant paired with wild-type KRAS.

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