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image: FDA Approves Second CAR T-Cell Therapy

FDA Approves Second CAR T-Cell Therapy

By Ashley P. Taylor | October 19, 2017

The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 

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image: Cancers Relapse by Feeding Off Immune Signals

Cancers Relapse by Feeding Off Immune Signals

By Shawna Williams | October 16, 2017

In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.

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image: Papers Based on Misidentified Cell Lines Top 32,000

Papers Based on Misidentified Cell Lines Top 32,000

By Kerry Grens | October 16, 2017

An analysis of contaminated literature finds that tens of thousands of papers used cell lines of questionable origins—and these were in turn cited by hundreds of thousands of other papers.

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image: Study Raises Questions About Patient-Derived Xenografts

Study Raises Questions About Patient-Derived Xenografts

By Ashley P. Taylor | October 10, 2017

When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.

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image: Image of the Day: Fragile Brain

Image of the Day: Fragile Brain

By The Scientist Staff | October 3, 2017

In Fragile X syndrome—a genetic mishap that results in cognitive delays—the lack of a translation-repressing protein leads to the rampant accumulation of other proteins in the mouse brain.

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image: Damage Patroller

Damage Patroller

By Anna Azvolinsky | October 1, 2017

Stephen Elledge has built a career studying how eukaryotic cells maintain genomic integrity.

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The 38-year-old synthetic biologist comes from a long line of tinkerers and engineers.

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image: Live Cell Extractions

Live Cell Extractions

By Ruth Williams | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By Shawna Williams | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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Pauses may help cells fine-tune gene expression.

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