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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Tracking Miracles

Tracking Miracles

By | April 1, 2015

A panel of oncologists discusses cases of exceptional responders, or cancer patients whose tumors disappear after a brief period of chemotherapy.

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image: Two-Faced RNAs

Two-Faced RNAs

By | April 1, 2015

The same microRNAs can have opposing roles in cancer.

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

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image: My Mighty Mouse

My Mighty Mouse

By | April 1, 2015

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

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image: Resisting Cancer

Resisting Cancer

By | April 1, 2015

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

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image: Opinion: Upgrading Cancer Prevention

Opinion: Upgrading Cancer Prevention

By | April 1, 2015

Preemptive detection and intervention will be key to easing the growing burden of cancer, particularly in developing countries.

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image: Opinion: Making Cancer Vaccines Work

Opinion: Making Cancer Vaccines Work

By | March 31, 2015

Armed with the right adjuvant system, vaccines are poised to tackle one of the world’s most intractable diseases. 

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Speaking of Science

Speaking of Science

By | March 1, 2015

March 2015's selection of notable quotes

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