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image: How Exercise Might Fight Cancer

How Exercise Might Fight Cancer

By | September 8, 2017

Epinephrine’s activation of the signaling pathway Hippo is responsible for the in vitro tumor-fighting effects of serum from women who worked out.

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Douglas Lowy and John Schiller, whose work led to the HPV vaccine, and Michael Hall, who discovered the TOR pathway, win this year’s prizes.

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image: Gilead to Pay Nearly $12B for CAR T-Cell Company

Gilead to Pay Nearly $12B for CAR T-Cell Company

By | August 28, 2017

The massive sum will buy out Kite Pharma, whose cancer therapy is expected to be among the first of its type approved by the FDA.

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image: Vitamin C Depletion Accelerates Leukemia in Mice

Vitamin C Depletion Accelerates Leukemia in Mice

By | August 21, 2017

High levels of vitamin C absorbed by blood-forming stem cells are important for their normal development. 

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image: Vitamin C Blocks Leukemia Progression in Mice

Vitamin C Blocks Leukemia Progression in Mice

By | August 17, 2017

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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image: Peer-Review Fraud Scheme Uncovered in China

Peer-Review Fraud Scheme Uncovered in China

By | July 31, 2017

The Chinese government finds almost 500 researchers guilty of misconduct in relation to a recent spate of retractions from a cancer journal.

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Mouse organoids reveal that a protein active during embryonic development joins forces with gene enhancers to revert cancer cells to an earlier developmental state.

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells Seek Out Tumors Based on Stiffness

Stem Cells Seek Out Tumors Based on Stiffness

By | July 26, 2017

The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.

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