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image: The Challenges of Precision

The Challenges of Precision

By Adam Marcus | April 1, 2015

Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.

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image: To Each His Own

To Each His Own

By Mary Beth Aberlin | April 1, 2015

Cancer treatment becomes more and more personal.


image: Toggling Between Life and Death

Toggling Between Life and Death

By Ashley P. Taylor | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.


image: Tracking Miracles

Tracking Miracles

By Jef Akst | April 1, 2015

A panel of oncologists discusses cases of exceptional responders, or cancer patients whose tumors disappear after a brief period of chemotherapy.


image: Two-Faced RNAs

Two-Faced RNAs

By Kerry Grens | April 1, 2015

The same microRNAs can have opposing roles in cancer.


image: From Many, One

From Many, One

By Elena E. Giorgi | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?


image: My Mighty Mouse

My Mighty Mouse

By Megan Scudellari | April 1, 2015

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

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image: Resisting Cancer

Resisting Cancer

By George Klein | April 1, 2015

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.


image: Opinion: Upgrading Cancer Prevention

Opinion: Upgrading Cancer Prevention

By David Lane | April 1, 2015

Preemptive detection and intervention will be key to easing the growing burden of cancer, particularly in developing countries.

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image: Hiding in Plain Sight

Hiding in Plain Sight

By Kim Smuga-Otto | March 31, 2015

Researchers using metagenomics and single-cell sequencing identify a potential new bacterial phylum.

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