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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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image: Immune Checkpoint Found Lacking in Type 1 Diabetes

Immune Checkpoint Found Lacking in Type 1 Diabetes

By | November 15, 2017

Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.

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image: Man Receives First In Vivo Gene-Editing Therapy

Man Receives First In Vivo Gene-Editing Therapy

By | November 15, 2017

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

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image: Cancer Researcher, Former AACR President Dies

Cancer Researcher, Former AACR President Dies

By | November 13, 2017

Donald Coffey, a longtime professor at Johns Hopkins University, discovered the nuclear matrix within cells and its role in DNA replication.

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The former chief of Eli Lilly USA is picked to replace Tom Price, who stepped down in September amid a controversy over the abuse of taxpayer-funded travel.

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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The report provides evidence that goes against concerns that Monsanto’s popular herbicide, Roundup, is carcinogenic. 

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Hormone Loss Prevents Obesity and Diabetes in Mice

Hormone Loss Prevents Obesity and Diabetes in Mice

By | November 6, 2017

Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.

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image: The Genetic Strategies of Dealing with High Altitude

The Genetic Strategies of Dealing with High Altitude

By | November 2, 2017

Andean highlander genomes possess cardiovascular-related variants, while populations from other regions evolved different solutions to manage the lack of oxygen.

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