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cancer

custom targeted cancer vaccine
Personalized Cancer Vaccines in Clinical Trials
Jasreet Hundal and Elaine R. Mardis | Jul 15, 2019 | 10+ min read
The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.
Does the Microbiome Help the Body Fight Cancer?
Catherine Offord | Jul 10, 2019 | 4 min read
Research in mice and humans is beginning to establish a link between the composition of microbes in the gut and immune responses to tumor cells, but the mechanisms are not yet clear.
MyHeritage Launches Health-Related Genetic Test, Ignites Debate
Catherine Offord | Jul 9, 2019 | 8 min read
Its screen for selected variants of some disease-linked genes gives customers an incomplete picture of their risk—do they know?
Henry Lynch obituary cancer genetics hereditary syndrome breast ovarian
Henry Lynch, Leader in Cancer Genetics, Dies
Chia-Yi Hou | Jun 7, 2019 | 2 min read
The Creighton University researcher discovered the genetic basis of hereditary breast-ovarian cancer syndrome.
Even Healthy Tissues Carry Clusters of Cells with Mutations: Study
Ashley Yeager | Jun 7, 2019 | 2 min read
Most of the genetic alterations are harmless, but some may contribute to cancer.
Cancer Leader LaSalle Leffall, Jr. Dies
Ashley Yeager | May 30, 2019 | 2 min read
The Howard University surgeon was the first African American president of the American Cancer Society and mentored thousands of medical students.
fat cells cachexia killer t cells
Cachexia Is Driven By Killer T Cells in a Mouse Model of Infection
Katarina Zimmer | May 22, 2019 | 5 min read
A new study reveals an unexpected role for the immune cells and a previously unknown mechanism for the wasting syndrome.
Genetically Personalized Fruit Flies Screen for Cancer Drugs
Ruth Williams | May 22, 2019 | 4 min read
Fly avatars bearing multiple genetic changes akin to those of a cancer patient lead to a tailor-made treatment that has shrunk the patient’s tumors.
clpp onc201 cancer mechanism of action clinical trial
Found: A Cancer Drug’s Mechanism of Action
Ashley P. Taylor | May 21, 2019 | 4 min read
As ONC201 moves through human clinical trials, scientists finally figure out that the compound and its analogs target a mitochondrial protease.
a CT scan of lungs
AI Accurately Detects Lung Cancer in Scans
Shawna Williams | May 21, 2019 | 2 min read
An artificial intelligence program called a neural network exceeds radiologists’ ability to detect malignancies, but more testing is needed before using the program clinically.
national cancer institute nci funding grants nanotechnology centers
National Cancer Institute Will Stop Funding Nanotechnology Centers
Chia-Yi Hou | May 20, 2019 | 1 min read
The Centers of Cancer Nanotechnology Excellence were established in 2005 through several phases of funding, which are reported to end next year.
Couple With Cancer Wins $2 Billion in Case Against Monsanto
Catherine Offord | May 14, 2019 | 2 min read
In determining that the illnesses came about from exposure to glyphosate in Roundup, a California jury delivers the biggest loss so far to the herbicide manufacturer in lawsuits about the product.
natural killer cells nk cell therapy product immunotherapy clinical trial
Clinical Trial Underway for a Natural Killer Cell Therapy
Chia-Yi Hou | May 7, 2019 | 3 min read
The cells, derived from induced pluripotent stem cells, are in testing as an immunotherapy for cancer patients with solid tumors.
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AI Uses Images and Omics to Decode Cancer
Amber Dance | May 1, 2019 | 10 min read
Machine learning can analyze photographs of cancer, tumor pathology slides, and genomes. Now, scientists are poised to integrate that information into cancer uber-models.
machine learning infographic
Infographic: How AI Analyzes Cancer
Amber Dance | May 1, 2019 | 1 min read
The latest machine learning models can identify many visual and molecular features of a particular cancer. If the technology advances to the clinic, it could help diagnose patients and predict survival.
t cell b cell lymphoma car t-cell therapy chimeric antigen receptor
A Revised CAR T for Lymphoma Has Fewer Side Effects
Kerry Grens | Apr 23, 2019 | 2 min read
An early-stage clinical study finds that none of the 25 patients treated developed neurotoxicity or cytokine release syndrome, common hazards of the cancer immunotherapy.
MD Anderson Cancer Center oust three researchers NIH
Three Researchers Ousted from MD Anderson
Chia-Yi Hou | Apr 22, 2019 | 2 min read
The center had received letters from NIH about researchers’ violations of granting agency policies and intellectual property theft in 2018.
sperm epigenetics cancer risk heritability histones
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Emma Yasinski | Apr 19, 2019 | 3 min read
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
an illustration of T cells attacking a cancer cell
Two Patients Treated with CRISPRed Cells in Immunotherapy Trial
Shawna Williams | Apr 16, 2019 | 1 min read
One person with multiple myeloma and one with sarcoma are the first so far to receive the genetically engineered T cells in the study.
nancy davidson fred hutch epigenetics breast cancer
Q&A: Epigenetic Therapies for Breast Cancer
Katarina Zimmer | Apr 4, 2019 | 4 min read
Breast cancer researcher and oncologist Nancy Davidson discusses what we’ve learned from the first wave of epigenetic trials for breast cancer, and what challenges lie ahead before such therapies reach the clinic.
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