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cancer

exterior of Fred Hutch research building
Fred Hutch Receives $710 Million Gift from the Bezos Family
Shawna Williams | Oct 13, 2022 | 1 min read
The donation will fund recruitment, research facilities, clinical research, and immunotherapy research.
Happy woman surrounded by children
Pediatric Oncologist Audrey Evans Dies at 97
Lisa Winter | Oct 12, 2022 | 3 min read
Evans advanced the field of pediatric cancer treatment and cofounded the first Ronald McDonald House in 1974 to help families with sick children.
Mind the Graph
Seeing Science: How to Visually Explain Complex Concepts
The Scientist and Mind the Graph | 4 min read
Scientists turn to an easy, plug-and-play platform to visually translate their work.
Lipid nanoparticle delivers treatment to a cancer cell.
Researchers Develop a CRISPR-Based Therapy That Penetrates Solid Tumors
Jennifer Zieba, PhD | Oct 10, 2022 | 3 min read
By packaging lipid nanoparticles with elements that decrease the fibrous nature of solid tumors, researchers can deliver CRISPR therapies in a more efficient manner.
outline of a brain slice with white patch surrounded by teal
Astrocytes Feed Glioblastoma, Promoting Tumor Growth: Mouse Study
Patience Asanga | Oct 5, 2022 | 3 min read
Starving glioblastoma tumors of the cholesterol made by astrocytes could suppress brain cancer progression.
Developing Effective Cell Therapies for Challenging Cancer Types 
Developing Effective Cell Therapies for Challenging Cancer Types
The Scientist | 1 min read
In this webinar, Sandhya Sharma will discuss how to enrich for antigen-specific T-cells to treat virus-associated malignancies.
Grayscale microscopic image of dying melanoma cells
Science Snapshot: Living Bubble Wrap
Lisa Winter | Oct 5, 2022 | 1 min read
This year’s fourth-place winner of the 2022 Nikon Small World in Motion competition shows dying melanoma cells.
Illustration of intestine containing pink microbes
Fungal DNA, Cells Found in Human Tumors
Catherine Offord | Sep 30, 2022 | 2 min read
It’s not clear whether, or how, the organisms might play a role in disease pathology.
Leveraging the Microbiome to Break Down Tumor Resistance
Leveraging the Microbiome to Break Down Tumor Resistance
The Scientist and PerkinElmer | 1 min read
Mat Robinson and Mark Tangney discuss how enhancing the efficacy of immune checkpoint inhibitors improves patient outcomes.
A full blood sample vial lying on top of a piece of paper that reads “Acute lymphoblastic leukemia”.
Targeting Leukemia with T Cells That Avoid Self-Destruction
Deanna MacNeil, PhD | Sep 26, 2022 | 3 min read
Researchers found that naturally-occurring CD7-negative T cells avoid self-destruction and are good effectors in CAR T therapy for T cell blood cancers.
A wrecking ball destroying a malignant cell as a 3D illustration
Armored CAR T Cells Break Through Immune Suppression in Solid Tumors
Jennifer Zieba, PhD | Sep 26, 2022 | 3 min read
Researchers determined the safety and antitumor ability of genetically engineered CAR T cells that circumvent immune suppression in a prostate cancer phase I clinical trial.
Overcoming T Cell Therapy Barriers with Engineered Proteins
Overcoming T Cell Therapy Barriers with Engineered Proteins
The Scientist | 1 min read
Shannon Oda will discuss how to develop novel engineered fusion proteins to improve T cell therapies against hematological and solid tumors.
jigsaw puzzle with magnifying glass over the word "metastasis" 
Breast Cancer Cells Retrain T Cells to Invade Specific Tissues
Nele Haelterman, PhD | Sep 26, 2022 | 3 min read
Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.
illustration of blue cells with exosomes budding off of them and floating away
Nanoparticles Spur Mouse Immune System to Attack Cancer
Shafaq Zia | Sep 13, 2022 | 2 min read
A study finds that engineered exosomes are effective in mice, but their potential use in humans raises safety questions.  
Reinvigorating the Immune System to Attack Cancer Cells Using Highly Specific Antibodies
Reinvigorating the Immune System to Attack Cancer Cells Using Highly Specific Antibodies
Fortis Life Sciences | 3 min read
Cancer immunotherapy targets the tumor microenvironment, blocking the molecular pathways that tumors exploit to prevent immune cell activity.
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker, PhD | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
Fluorescent microscopy of a healthy intestinal organoid and a tumor spheroid
Internal Clock Disruptions Increase Colon Cancer Risk in Mice
Shafaq Zia | Aug 19, 2022 | 3 min read
Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.
Technique Talk: Understanding Cancer One Base Edit at a Time
Technique Talk: Understanding Cancer One Base Edit at a Time
The Scientist | 1 min read
Francisco J. Sánchez-Rivera will discuss strategies to design CRISPR base editor libraries for in vivo applications.
Photograph of Humsa Venkatesh
Humsa Venkatesh Probes Cancer’s Grip on the Brain
Maddie Bender | Aug 15, 2022 | 3 min read
At Brigham and Women’s Hospital, the cancer biologist is combining research into the tumor microenvironment with the principles of neuroscience to tease apart how cancers grow—and how to stop them.
Monica Bertagnolli standing in a hallway
White House Names Monica Bertagnolli as NCI Director
Andy Carstens | Aug 10, 2022 | 2 min read
The announcement confirms earlier reports that Bertagnolli will become the first woman to lead the National Cancer Institute since its founding in 1937.
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