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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By Catherine Offord | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By Stephen P. Schoenberger and Ezra Cohen | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: Infographic: Antibody Cancer Therapy

Infographic: Antibody Cancer Therapy

By Ruth Williams | April 1, 2017

An experimental technique removes T cells that aid in vitro tumor growth.

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image: Infographic: Targeting Cancer Antigens

Infographic: Targeting Cancer Antigens

By Stephen P. Schoenberger and Ezra Cohen | April 1, 2017

Neoantigens may serve as valuable targets for new immunotherapies.

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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By Ruth Williams | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

By Anna Azvolinsky | March 30, 2017

Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.

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image: Experimental MERS Treatments Target Host Cell Receptor

Experimental MERS Treatments Target Host Cell Receptor

By Ashley Yeager | March 30, 2017

Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.

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image: Paralyzed Man Moves Arm with Neuroprosthetic

Paralyzed Man Moves Arm with Neuroprosthetic

By Jef Akst | March 30, 2017

Two chips implanted in a quadriplegic patient’s motor cortex and 36 electrodes in his right arm allow the man to control the movement of his right arm and hand.

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The University of Rhode Island neurotoxicologist and dean came to the U.S. for college in the 1980s. 

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image: Consilience, Episode 2: In Tune

Consilience, Episode 2: In Tune

By Ben Andrew Henry | March 21, 2017

Ben Henry delves into the still-unanswered questions of where our musical preferences come from and what makes synesthetes tick.

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