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image: Human Genetic Variation May Complicate CRISPR

Human Genetic Variation May Complicate CRISPR

By | July 31, 2017

Slight sequence differences confound target sites in precision genome-editing, a study shows.

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Another case of HIV remission emerges, this time in a South African girl diagnosed as an infant and disease-free for more than eight years.

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image: Mammalian Immunity: What’s RNAi Got to Do with It?

Mammalian Immunity: What’s RNAi Got to Do with It?

By | July 21, 2017

A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.

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image: Most of Human Genome Nonfunctional: Study

Most of Human Genome Nonfunctional: Study

By | July 17, 2017

An estimate derived from fertility rates concludes that at least 75 percent of our DNA has no critical utility.

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Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.

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The International Mouse Phenotyping Consortium aims to characterize the entire mouse genome, starting first with more than 3,300 genes. 

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image: T Cells That Drive Toxic Shock in Mice Identified

T Cells That Drive Toxic Shock in Mice Identified

By | June 20, 2017

Overzealous activity by mucosa-associated invariant T (MAIT) cells in response to bacterial toxins can lead to illness instead of stopping it.

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Research shows that human immunity develops much earlier than previously thought, but functions differently in adults.

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The publicly available database found nearly a third of samples included mutations targeted by either approved drugs or therapies in clinical trials. 

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image: Pinpointing the Culprit

Pinpointing the Culprit

By | June 1, 2017

Identifying immune cell subsets with CyTOF

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