Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.

A new study confirms reports of membrane-bound RNA molecules and points to their role in neutrophil migration.

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.

In Chapter 10, “Deep Discovery,” author Eric Topol considers the marriage of omics and AI.

To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.

A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.