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tag sanger institute disease medicine
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD
| Dec 4, 2023
| 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
FDA Approves Oral Drug for Fabry Disease
Ashley Yeager
| Aug 13, 2018
| 2 min read
The medicine increases the activity of a deficient enzyme in certain patients with the condition.
Pancreatic Organoids Take the Stage
Laura Tran, PhD
| Dec 1, 2023
| 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski
| Nov 9, 2021
| 4 min read
A key mutation turns healing cells into cancer promoters.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD
| Sep 8, 2023
| 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Chronic Fatigue Syndrome Reframed
Kerry Grens
| Feb 11, 2015
| 2 min read
To more accurately reflect the condition, the Institute of Medicine recommends renaming it systemic exertion intolerance disease.
Integrate and Innovate with NGS and Multiomics
The Scientist
and Illumina
| May 4, 2023
| 6 min read
Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.
Transposons Identified as Likely Cause of Undiagnosed Diseases
Jef Akst
| Jan 13, 2020
| 4 min read
A tool for identifying jumping gene insertions in DNA sequencing data turns up possible explanations for four patients’ rare developmental disorders.
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