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tag bumble bees genetics genomics

A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Toward a “Clickable Plant”
Jane Salodof Macneil | Feb 15, 2004 | 9 min read
By conscious design, plant genomics initiatives have devoted initial resources to new technology development. Part of that money went to developing functional genomics approaches, and part to new sequencing technologies.
Whole-Genome SNP Genotyping
Marilee Ogren | Jun 1, 2003 | 8 min read
Clockwise from top left: images courtesy of Affymetrix, Illumina, Sequenom and Illumina Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease susceptibility, environmental response, and drug metabolism. Researchers are understandably keen to dissect these variations, most of which take the form of single-nucleotide polymorphisms (SNPs). A SNP (pron
Techniques for Assessing Genomic Copy Number Variations
Sarah C.P. Williams | Oct 1, 2016 | 8 min read
As the importance of genomic copy number variations for health and disease becomes clearer, researchers are creating new ways to detect these changes in the genome.
Beyond Sanger: Toward the $1,000 Genome
Aileen Constans | Jun 29, 2003 | 10 min read
Courtesy of Solexa Total Genotyping Without a doubt, the quarter-century-old Sanger sequencing method performed like a champ during the Human Genome Project. But with the capacity to read only a few hundred bases per reaction, it is far too slow and expensive for routine use in clinical settings. Reaping the rewards of the genomics era will clearly require faster and cheaper alternatives. Some companies estimate that within the next five years, technical advances could drop the cost of seque
Yeast Proteomics Milestone
Aileen Constans | Dec 14, 2003 | 4 min read
Courtesy of Won-Ki Huh  LOCAL COLOR: Researchers used librar-ies of tagged proteins to determine where those proteins accumulate, and to what levels. Shown are representative localization (top) and co-localization (bottom) data. Researchers from the University of California, San Francisco, have probed the yeast proteome in the highest level of detail to date. Using sets of fusion-tagged proteins, the scientists, led by Howard Hughes Medical Institute investigators Erin O'Shea and Jonatha
Research Briefs
Maria Anderson | Oct 19, 2003 | 4 min read
Research Briefs New Genes: The Ears Have 'Em; The Worker, The Soldier, The Candlestick Maker; For Genomes Without Borders, Biobanks Unite New genes: The ears have 'em While scouring a new cDNA library, researchers in the Netherlands discovered 80 novel expressed-sequence tags, including 25 preferentially expressed in human fetal cochlea.1 The researchers from the University Medical Center in Nijmegen (UMCN) found that 155 ESTs map to loci for nonsyndromic deafness, which is not associated
Yeast Pushes the Proteomic Envelope
Mignon Fogarty | Jul 27, 2003 | 7 min read
 NETWORKED: (A) Effects of the gal4D+gal perturbation are superimposed on a gene interaction network… Click for larger version (92K) Large-scale biology once conjured images of brute-force genetic screens resulting in collections of mutants. More recently, it has meant genome sequencing on unprecedented scales. But today, as this issue's Hot Papers demonstrate, the leading edge in large-scale biology is proteomics. As in the large-scale efforts of the past, researchers rely on simp

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