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tag recombination culture genetics genomics
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
The Cre-
loxP
System: A Powerful Tool in the Genetic Toolbox
Laura Tran, PhD
| Dec 4, 2023
| 9 min read
Standing at the cornerstone of genetic research, Cre-
loxP
recombination serves as molecular scissors for precisely manipulating the genome.
Cellular Competence: Making Recombinant DNA Accessible
Nathan Ni, PhD
| Jun 1, 2023
| 2 min read
Coaxing bacteria into taking up recombinant DNA was arduous until Douglas Hanahan took action.
A Sticky Situation: Recombinant DNA Technology
Kathryn Loydall, PhD
| May 1, 2023
| 5 min read
Janet Mertz’s work with simian virus 40 DNA during her graduate years was pivotal for developing DNA recombination as we now know it.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
Bio-Rad Launches Vericheck ddPCR Replication Competent Lentivirus and Replication Competent AAV Kits for Cell and Gene Therapy Production
Bio-Rad Laboratories
| Feb 27, 2024
| 2 min read
Rapid, Sensitive, and Validated Detection of Viral Replication Genes Using Droplet Digital™ PCR During Cell and Gene Therapy Production
One Protein to Rule Them All
Shelby Bradford, PhD
| Feb 28, 2024
| 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD
| Feb 21, 2024
| 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
A Journey Into the Brain
Danielle Gerhard, PhD
| Mar 22, 2024
| 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
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