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tag heart failure evolution disease medicine microbiology developmental biology

An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
Updated Sept 1
coronavirus pandemic news articles covid-19 sars-cov-2 virology research science
Follow the Coronavirus Outbreak
The Scientist | Feb 20, 2020 | 10+ min read
Saliva tests screen staff and students at University of Illinois; Study ranks species most susceptible to SARS-CoV-2 infection; COVID-19 clinical trials test drugs that inhibit kinin system
Of Cells and Limits
Anna Azvolinsky | Mar 1, 2015 | 9 min read
Leonard Hayflick has been unafraid to speak his mind, whether it is to upend a well-entrenched dogma or to challenge the federal government. At 86, he’s nowhere near retirement.
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
Longevity
Jill Adams(juadams@the-scientist.com) | May 8, 2005 | 7 min read
During autophagy-literally "self-eating"-cells deliver cytoplasmic constituents, including whole organelles, to the lysosome for degradation.
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat

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