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tag enzymes culture

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Cas9 enzyme
Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control
Ida Emilie Steinmark, PhD | Apr 26, 2023 | 3 min read
In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.
Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021 | 3 min read
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
a human neuron illuminated in bright green on a black background.
Mitochondrial Metabolism Dictates Neurons’ Growth Rate
Katherine Irving | Jan 30, 2023 | 4 min read
Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.
Keeping Tabs on Cultured Cells
Lissa Harris(lharris@the-scientist.com) | Mar 13, 2005 | 6 min read
THE CULTURE WITHIN:Photo courtesy of Drs. C.C. Uphoff and H.G. Drexler, DSMZ-German Collection of Microorganism and Cell Cultures, Braunschweig, GermanyHeLa cell line infected with Mycoplasma hyorhinis. Scanning electron micrograph of critical point-dried cell culture grown on cover slips. Note the loop- and rod-like mycoplasmas attached to the host cell membrane. Smaller web-like structures on the cell surface represent microvilli of the cell. Original magnification 3,000×.Mycoplasmas have
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Better Understanding Of Cell's Life Eases Culturing
Ricki Lewis | Nov 13, 1994 | 10+ min read
"Lots of companies come out with media or reagents for this or that, and make a big splash, but they're all basically derivatives of traditional products," says Hayden Coon, a former National Institutes of Health re-searcher who is the founder of Human Cell Therapies Inc. of Chebeague Island, Maine. Advanced Biotechnologies Inc. Columbia, MD American Qualex Antibodies La Mirada, CA American Type Culture Collection (ATCC) Rockv
Better Understanding Of Cell's Life Eases Culturing
Ricki Lewis | Nov 13, 1994 | 10+ min read
"Lots of companies come out with media or reagents for this or that, and make a big splash, but they're all basically derivatives of traditional products," says Hayden Coon, a former National Institutes of Health re-searcher who is the founder of Human Cell Therapies Inc. of Chebeague Island, Maine. Advanced Biotechnologies Inc. Columbia, MD American Qualex Antibodies La Mirada, CA American Type Culture Collection (ATCC) Rockv
Luminescence Developments Help Scientists See The Light
James Kling | May 11, 1997 | 9 min read
Biologists are constantly seeking more sensitive assays to detect the presence of organisms or telltale DNA, RNA, and proteins. Although radioactive tags incorporated into the target itself (or into a complementary strand)-and later detected by Geiger counters or film exposures-have traditionally given good sensitivity, the problems of waste disposal and laboratory monitoring have driven a search for alternative tags that have radioactivity's sensitivity but avoid its hazards. Fluorescent tags-

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