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image: Immune Checkpoint Found Lacking in Type 1 Diabetes

Immune Checkpoint Found Lacking in Type 1 Diabetes

By | November 15, 2017

Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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image: Hormone Loss Prevents Obesity and Diabetes in Mice

Hormone Loss Prevents Obesity and Diabetes in Mice

By | November 6, 2017

Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.

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image: FDA Approves Second CAR T-Cell Therapy

FDA Approves Second CAR T-Cell Therapy

By | October 19, 2017

The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 

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image: Compound Found in Red Wine Boosts Immune Cell Function

Compound Found in Red Wine Boosts Immune Cell Function

By | October 17, 2017

At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 

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image: Cancers Relapse by Feeding Off Immune Signals

Cancers Relapse by Feeding Off Immune Signals

By | October 16, 2017

In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.

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A needle-free alternative to the finger-prick test would be a godsend for many sufferers of diabetes, but the industry has yet to clear the technological hurdles.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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image: Infographic: Macrophages Around the Body

Infographic: Macrophages Around the Body

By | October 1, 2017

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.

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image: Macrophages Are the Ultimate Multitaskers

Macrophages Are the Ultimate Multitaskers

By | October 1, 2017

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

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