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tag male infertility evolution genetics genomics

a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
It Takes Two
Jef Akst | Nov 21, 2013 | 3 min read
Two genes from the Y chromosome are sufficient to generate male mice capable of fathering healthy offspring via an assisted reproductive technique.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
A colorful mandarinfish on a reef
Genome Spotlight: Mandarinfish (Synchiropus splendidus)
Christie Wilcox, PhD | Oct 28, 2021 | 3 min read
The high-quality genome sequence sheds light on the colorful nature of these popular aquarium fish.
illustration of a mitochondrian inside a cell
Could Dad’s Mitochondrial DNA Benefit Hybrids?
Alejandra Manjarrez, PhD | Jan 20, 2022 | 7 min read
Studies have found that organisms can inherit mitochondria from male parents in rare instances, and both theoretical and experimental work hint that this biparental inheritance is more than just a fluke.
A Benefit of Failed Pregnancy?
Ruth Williams | Apr 9, 2015 | 3 min read
Scientists find a common genetic variant in mothers that decreases the chance of successful pregnancy.
Sly Guys
The Scientist | Jul 1, 2014 | 10+ min read
Across the animal kingdom, dominance isn’t the only way for a male to score. Colluding, sneaking around, or cross-dressing can work, too.
Flies Invade Human Genetics
Ricki Lewis | Jun 21, 1998 | 9 min read
  DOUBLE WINGS: An ultrabithorax mutant fly has a total duplication of the body segment that carries wings. Recent issues of The American Journal of Human Genetics have featured a newcomer: Drosophila melanogaster. The fruit fly is a frequent star of a series of review articles called "Insights From Model Systems." The insect's appearance in a human genetics journal is a telling sign that this model among model organisms, long used to decipher the general principles of inheritance
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
A Personal View of Genomics
Ricki Lewis | Nov 25, 2001 | 6 min read
It wasn't easy getting to the 4th International Meeting on Single Nucleotide Polymorphisms and Complex Genome Analysis held Oct. 10-15 at the Wenner-Gren Foundation in Stockholm. A week earlier, as flight cancellations continued in the wake of the Sept. 11 terrorist attacks, SwissAir had declared bankruptcy and an SAS jet had crashed in Milan, further disrupting schedules. So it was little surprise that several speakers had to phone in their talks. But not J. Craig Venter, president and chief sc

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