With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Barcodes of mRNA travel to the cells' axon terminals, offering a sequencing-based approach to neural mapping.

Date: February 2, 1998 Chart 1 Chart 2 Prokaryotic expression systems, reviewed in the September 1, 1997, issue of The Scientist were part of the early repertoire of research tools in molecular biology. Although the expression of recombinant protein in prokaryotes provided a means to develop other research tools (antibodies, for example ) and study basic aspects of biological function, the scope and depth of this research were limited, especially with regard to eukaryotic proteins. The de novo

Scientists have found a way to reactivate a gene in mice that is silenced in a neurodevelopmental disorder called Angelman syndrome.

Transcription factor levels dictate which neurons in a network store a memory.

The pandemic spurred innovation in a variety of ways, from CRISPR-based diagnostics to cell biology benchwork at home.

From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.

Sidebar: Society for Neuroscience NEW MESSENGERS: Caltech’s Erin Schuman and colleagues discovered that one form of nitric oxide is important to long-term potentiation. Can you recall where you were when you heard about the explosion of the space shuttle Challenger? Why is it that, almost universally, people can remember with vivid and instantaneous detail this tragic event when they can't recall what they had for dinner just days before? How are some memories indelibly hard-wired into o

Content Jumping DNA Semen pharming Screening for heart risk Real-time signaling PubSCIENCE starts, PubMedCentral grows When time stands still Shutting down the pump Brain gain JUMPING DNA Mutations aren't transmitted only by inheritance--they can cross species, too, according to recent findings by John F. McDonald, head of the genetics department at the University of Georgia (I.K. Jordan et al., "Evidence for the recent horizontal transfer of long terminal repeat retrotransposon," Proceedings of

When scientists make long-term research plans, they must try to anticipate how emerging technologies will influence their work in the coming years.