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tag receptor microbiology disease medicine culture cell molecular biology
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Viral Protein Behind Chronic Inflammation in People with HIV: Study
Natalia Mesa, PhD
| Dec 12, 2022
| 3 min read
The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A Journey Into the Brain
Danielle Gerhard, PhD
| Mar 22, 2024
| 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Are Phages Overlooked Mediators of Health and Disease?
Catherine Offord
| Feb 1, 2021
| 10+ min read
Bacteria-infecting viruses affect the composition and behavior of microbes in the mammalian gut—and perhaps influence human biology.
Combating COVID-19 with Cell-Free Expression
The Scientist
| Aug 19, 2020
| 6 min read
Scientists rely on synthetic biology and cell-free expression systems for developing novel approaches to combat the pandemic.
Pancreatic Organoids Take the Stage
Laura Tran, PhD
| Dec 1, 2023
| 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD
| Sep 14, 2023
| 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD
| Aug 31, 2022
| 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Cooperation and Cheating
Mariella Bodemeier Loayza Careaga, PhD
| Jun 1, 2023
| 6 min read
Bacteria cooperate to benefit the collective, but cheaters can rig the system. How is the balance maintained?
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