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tag double strand breaks cell molecular biology culture

3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD | Oct 10, 2022 | 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
Does DNA Damage Cause Cancer?
Charles Q. Choi | Jun 1, 2007 | 4 min read
Back-to-back studies pose double-strand breaks as initiating tumorigenesis.
Conceptual vector illustration depicting CRISPR gene editing by scientists for medical applications.
Optimizing Gene Editing with PARP1 CRISPR Plasmids 
The Scientist and Santa Cruz Biotechnology, Inc. | Jan 24, 2024 | 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.   
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Seeing Double
Nicholette Zeliadt | Nov 1, 2013 | 7 min read
Combining two imaging techniques integrates molecular specificity with nanometer-scale resolution.
 
All Roads Lead to Genome Editing
Danielle Gerhard, PhD | Feb 9, 2024 | 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Top 7 in molecular biology
Megan Scudellari | Feb 28, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology and related areas, from Faculty of 1000
Top 7 in molecular biology
Megan Scudellari | Jun 14, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000.
3D structural model of a Cas protein and sgRNA targeting and unwinding DNA for gene editing.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD | Nov 29, 2023 | 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.

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