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tag double strand breaks cell molecular biology culture
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD
| Oct 10, 2022
| 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
Does DNA Damage Cause Cancer?
Charles Q. Choi
| Jun 1, 2007
| 4 min read
Back-to-back studies pose double-strand breaks as initiating tumorigenesis.
Optimizing Gene Editing with PARP1 CRISPR Plasmids
The Scientist
and Santa Cruz Biotechnology, Inc.
| Jan 24, 2024
| 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Seeing Double
Nicholette Zeliadt
| Nov 1, 2013
| 7 min read
Combining two imaging techniques integrates molecular specificity with nanometer-scale resolution.
All Roads Lead to Genome Editing
Danielle Gerhard, PhD
| Feb 9, 2024
| 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Top 7 in molecular biology
Megan Scudellari
| Feb 28, 2011
| 3 min read
A snapshot of the most highly ranked articles in molecular biology and related areas, from Faculty of 1000
Top 7 in molecular biology
Megan Scudellari
| Jun 14, 2011
| 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD
| Nov 29, 2023
| 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
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