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tag double strand breaks disease medicine cell molecular biology
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
DNA Damage Linked to Brain Overgrowth in Autism
Abby Olena, PhD
| Feb 5, 2020
| 4 min read
Cell lines from individuals with macrocephalic autism spectrum disorder have an increased number of double-strand breaks in the DNA of long neural genes.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Top 7 in molecular biology
Megan Scudellari
| Feb 28, 2011
| 3 min read
A snapshot of the most highly ranked articles in molecular biology and related areas, from Faculty of 1000
Top 7 in molecular biology
Megan Scudellari
| Jun 14, 2011
| 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD
| Nov 29, 2023
| 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
Whenever, Wherever: Taking DNA Amplification Outside the Lab
Hannah Thomasy, PhD
| Dec 4, 2023
| 10 min read
Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.
New “Prime Editing” Method Makes Only Single-Stranded DNA Cuts
Emma Yasinski
| Oct 21, 2019
| 4 min read
In demonstrations in cell lines, the technique has a similar efficacy to CRISPR-Cas9, but fewer off-target effects.
Aging and Cancer
Rebecca Roberts, PhD
| Nov 14, 2023
| 6 min read
The relationship between aging and cancer is complex, with several shared underlying mechanisms.
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