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Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
DNA, disease & medicine, genetics & genomics
New Map Charts Genetic Expression Across Tissue Types, Sexes
Ashley Yeager | Sep 10, 2020 | 3 min read
A decade-long effort to probe gene regulation reveals differences between males and females, points to essential regulatory elements, and offers insight into past work on telomeres.
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Chia-Yi Hou | Sep 1, 2019 | 3 min read
The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.
In Our Blood: A Profile of Stuart Orkin
Anna Azvolinsky | Jul 15, 2019 | 9 min read
By unraveling the molecular underpinnings of inherited blood disorders, the Boston Children’s Hospital researcher has provided the basis for therapies now being tested for beta-thalassemia and sickle cell disease.
Allele Shows Pyrethroid Resistance’s Spread in African Mosquitos
Carolyn Wilke | Mar 22, 2019 | 4 min read
Researchers can now track the expansion of a resistance mechanism that allows the malaria vector Anopholes funestus to detoxify a key insecticide used on bed nets.
Electric Shock Allows for CRISPR Gene Editing Without a Viral Vector
Ashley Yeager | Jul 12, 2018 | 2 min read
Brief electroporation appears to make T cells more receptive to new genetic material, which could speed the development of immunotherapies.