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tag self sacrifice disease medicine

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
vaccine, Covid-19, coronavirus, SARS-CoV-2, pandemic, self experimentation, polio, poliovirus, yellow fever, Jonas Salk, Joseph Goldberger, George Church
Self-Experimentation in the Time of COVID-19
Amanda Heidt | Aug 6, 2020 | 6 min read
Scientists are taking their own vaccines, an ethically murky practice that has a long and sometimes celebrated history in medicine.
Lighting Up Life in Real Time
Aileen Constans | Jun 9, 2002 | 2 min read
In recent years scientists have exploited the light-generating capability of luciferase in applications ranging from apoptosis detection to DNA quantitation. Now Alameda, Calif.-based Xenogen has taken this useful enzyme one step further, with a luciferase-based system for studying infectious diseases, cancer, and metabolic diseases in living animals in real time. Xenogen has developed Bioware™ animal models, in which pathogens, target genes, or tumor cells are tagged with luciferase, whi
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Longevity
Jill Adams(juadams@the-scientist.com) | May 8, 2005 | 7 min read
During autophagy-literally "self-eating"-cells deliver cytoplasmic constituents, including whole organelles, to the lysosome for degradation.
Building Nanoscale Structures with DNA
Arun Richard Chandrasekaran | Jul 16, 2017 | 10+ min read
The versatility of geometric shapes made from the nucleic acid are proving useful in a wide variety of fields from molecular computation to biology to medicine.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Scientist as Subject
Amanda Heidt | Oct 1, 2020 | 3 min read
In the past, it was not uncommon for researcher to test their experimental therapeutics and vaccines on themselves. Some even volunteered to be exposed to pathogen-carrying vectors.
The AIDS Research Evaluators
Lynn Gambale | Jul 9, 1995 | 6 min read
Chairman: Arnold Levine, chairman, department of molecular biology, Princeton University Barry Bloom, Weinstock Professor and Howard Hughes Medical Institute (HHMI) investigator, department of microbiology and immunology, Albert Einstein College of Medicine, New York Rebecca Buckley, professor of pediatrics and immunology, Duke University Medical Center Charles Carpenter, chairman, Office of AIDS Research Advisory Committee; professor of medicine,Brown University School of Medicine Don

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